61. You generate a hypothetical mutant mouse in which dendritic cells or macrophages cannot interact with CTL. You infect this mouse with LCMV and follow the infection over time. You compare this to a control experiment in which you infected a normal (unaltered) mouse with LCMV. Based on what was covered in the course, what do you expect to observe? Group of answer choices (A) The mouse will live without pathology (B) The mouse develops strong pathology (C) The number of CTL will be higher in the mutant compared to the normal mouse (D) B and C (E) Non-lytic immune responses will fail, resulting in a larger number of CTL
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Step 1: Dendritic cells and macrophages play a crucial role in presenting antigens to cytotoxic T lymphocytes (CTL) and activating them to kill infected cells. Show more…
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