A 10-month-old boy has a history of severe, frequent viral and bacterial infections. He is awaiting a bone marrow transplant. Flow cytometry shows that the lymphocytes lack both the T-lymphocyte and B-lymphocyte receptors, but they express natural killer cell markers. A defect in which of the following best explains this patient's condition? A) Bruton tyrosine kinase B) CD8 antigen C) Complement C2 gene D) Recombinase-activating gene 1 E) Thymus development
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Flow cytometry shows that his lymphocytes lack both T-lymphocyte and B-lymphocyte receptors, but they express natural killer cell markers. This indicates a problem with the development of both T and B cells, which are crucial for adaptive immunity. A) Bruton Show more…
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