Question

A gene contains three exons (A, B, C) and two introns. This gene is expressed heavily in muscle cells as well as neurons in the body; you find lots of A proteins in these two tissue types. a) Draw out a schematic of this eukaryotic gene, labeling all components. b) In looking at A proteins expressed in the tissue types, you find that the amino acid sequence differs slightly between the muscle and the neurons. Specifically, the amino acid sequence at the beginning of both proteins is identical, but the amino acid sequence near the end of the protein is quite different between the two tissue types. Briefly explain how this is possible. (1-2 sentences) - I know this is alternative splicing c) Based on what you know about A, draw out a schematic of what the mature mRNA would look like in neurons.

          A gene contains three exons (A, B, C) and two introns. This gene is expressed heavily in muscle cells as well as neurons in the body; you find lots of A proteins in these two tissue types.
a) Draw out a schematic of this eukaryotic gene, labeling all components.
b) In looking at A proteins expressed in the tissue types, you find that the amino acid sequence differs slightly between the muscle and the neurons. Specifically, the amino acid sequence at the beginning of both proteins is identical, but the amino acid sequence near the end of the protein is quite different between the two tissue types. Briefly explain how this is possible. (1-2 sentences) - I know this is alternative splicing
c) Based on what you know about A, draw out a schematic of what the mature mRNA would look like in neurons.

Added by Barbara D.

Question

Please give Ace some feedback