A mutation in DNA generates a UGA stop codon in the middle of the mRNA coding for a particular protein. A second mutation in the cell's DNA leads to a single nucleotide change in a tRNA that allows the correct translation of the protein; that is, the second mutation "suppresses" the defect caused by the first. The altered tRNA translates the UGA as tryptophan. What nucleotide change has probably occurred in the mutant tRNA molecule? What consequences would the presence of such a mutant tRNA have for the translation of the normal genes in this cell?
Added by Jenny S.
Close
Step 1
** Show more…
Show all steps
Your feedback will help us improve your experience
Shaiju T and 71 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Josee P.
A mutation in DNA generates a UGA stop codon in the middle of the mRNA coding for a particular protein. A second mutation in the cell's DNA leads to a single nucleotide change in a tRNA that allows the correct translation of this protein; that is, the second mutation 'suppresses" the defect caused by the first. The altered tRNA translates the UGA as tryptophan. What nucleotide change has probably occurred in the mutant tRNA molecule? What consequences would the presence of such a mutant tRNA have for the translation of the normal genes in this cell?
Describe some ways in which DNA is altered to cause mutations. Consider the following segment in mRNA produced by the normal order of DNA nucleotides: - CAU UCU CGA GUU- - a. What is the amino acid order produced from this mRNA? b. What is the amino acid order if a mutation changes CUU to CCU? c. What is the amino acid order if a mutation changes CGA to UGA? d. What happens to protein synthesis if a mutation changes UCU to UGU? e. What happens if a G is added to the beginning of the mRNA segment? f. What happens if the $C$ is removed from the beginning of the mRNA segment?
Nucleic Acids and Protein Synthesis
Genetic Mutations
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD