Another way to decrease the microbial load on humans is through medicine. There are five methods of drug action against microbes. Match the mechanism with the description of the specific drug. penicillin inhibits one of the enzymes that synthesizes the cell wall Sulfa drugs block folic acid production Polymyxin B makes holes in the membrane Tetracycline binds to rRNA Quinolones prevent the two DNA helices from pulling apart from each other
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- Penicillin inhibits one of the enzymes that synthesizes the cell wall. - Sulfa drugs block folic acid production. - Polymyxin B makes holes in the membrane. - Tetracycline binds to rRNA. - Quinolones prevent the two DNA helices from pulling apart from each Show more…
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What are some strategies scientists use to counter microbial mechanisms of drug resistance? Choose one or more: A using only bactericidal (not bacteriostatic) antibiotics when adding to animal feed B. administering a drug with a decoy for the microbial inactivating enzyme C modifying the drug to increase its minimum inhibitory concentration (MIC) D. chemically modifying the drug to prevent inactivation by microbial enzymes E: increasing the length of time during which a patient is treated with a given antibiotic
Antimicrobial Drug Mode of action Penicillin Affects peptidoglycan to cause cell wall damage and lysis Chloramphenicol Inhibits protein synthesis by binding to 70S ribosomes Binds to ergosterol to affect cell membrane Amphotericin B Quinines Causes buildup of toxic free radicals in parasite's cells Oseltamivir Prevents viral budding Refer to the table given above to answer the following: A) Which of the drugs given in the table above could be used to treat yeast infection with selective toxicity? B) Explain why your choice of antimicrobials would be selectively toxic: C) Explain why you eliminated all the other choices of antimicrobials.
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