Anterograde transport______ O refers to protein synthesis in the axon O refers to neurotransmitter signaling between astrocytes O refers to transport from the synapse to the cell body O refers to transport in the axon O refers to transport down to the cell body
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Step 1: Anterograde transport refers to the movement of substances from the cell body (soma) down the axon towards the axon terminal. Show more…
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QUESTION 24: Which of the following accurately describes the route a secreted protein would take from synthesis to secretion? Translation in the rough ER (rER), followed by transport through the ER and then the Golgi apparatus, packaging into vesicles in the Golgi, transport along microtubules to the plasma membrane, exocytosis. Translation in the smooth ER, followed by transport through the ER and then the Golgi apparatus, packaging into vesicles in the Golgi, transport along microtubules to the plasma membrane, exocytosis. Translation in the Golgi apparatus, followed by transport through the ER and then packaging into vesicles, transport along microtubules to the plasma membrane, exocytosis. None of the above. QUESTION 25: Match the route of neurotransmitter signaling in the postsynaptic cell with its description: Fastest form of synaptic transmission - A. Ligand-gated ion channels. Uses amplification via enzymes to provide slower and more sustained modulation of postsynaptic neurons - B. GPCRs and second messenger signaling. Shortcut pathway - C. GPCRs activate G-proteins that gate ion channels.
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Translocation of most proteins into the ER requires all of the following EXCEPT a(n): a. SRP receptor b. signal recognition particle c. importin receptor d. ribosome e. signal sequence 2. Which of the following describes a transporter that requires ATP hydrolysis to move solute A and solute B out of the cell? a. an active symport b. an active antiport c. a passive symport d. an active uniport e. a passive antiport 3. A vesicle traveling down an axon on a microtubule towards a synapse is being pulled by which type of motor? a. dynein b. myosin c. filamin d. kinesin e. actin
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1. Myelin is important for: a) Insulating the dendrites and synaptic EPSPs. b) Preventing the axon terminals from releasing transmitters inappropriately. c) Organizing the glutamate receptors on the axon. d) Restricting sodium channel diffusion on the axon. 2. If you treat cells as above but do not wait longer for the receptors and ligands to proceed down the endosomal pathway, what might you now observe under the microscope? a) Red dots in the cell but no green dots. b) Green dots in the cell but no red dots. c) No dots in the cells. d) Red and green overlapping dots. 3. A surface transmembrane protein, when it's in a transport vesicle, has a certain topology. The extracellular domain of the protein, when found in a transport vesicle, would be located in the: a) Cytoplasm. b) Lumen of the vesicle. c) It must be cleaved off to enter the vesicle. d) Mitochondrion. 4. An intracellular pool of glutamate receptors, ready to be inserted into the postsynaptic membrane, can be found within a type of _____ inside the postsynaptic compartment. a) Golgi apparatus. b) Endoplasmic reticulum. c) ER-golgi intermediate complex. d) Endosome. e) Lysosome. 5. A type I transmembrane protein has: a) Its amino terminus in the ER lumen. b) Its carboxyl terminus in the ER lumen. c) Its carboxy terminus on the outside of the cell. d) Both amino and carboxy termini are outside the cell. 6. In polarized epithelial cells, different surface proteins are found on the apical and basal sides. There are 2 possibilities for how they get sorted correctly. One is direct trafficking and sorting from the trans-Golgi to the cell surface. The other pathway involves: a) Direct trafficking from the ER. b) Trafficking from endosomes. c) Trafficking from mitochondria. d) Trafficking from the nucleus.
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