A drug dealer from New York City was tested and found to be HIV positive and was counseled on precautions that he should take in his relationships to avoid infecting others. He moved to a small city and often trade drugs for sex. Over the course of several years, he had unprotected sex with 48 young women. His HIV status became known and the man was found guilty of reckless endangerment and statutory rape and was sentenced to years in prison.
a. What tests should be done to determine whether these young women are infected?
b. The 1st screening test results were positive for 39 of the 48 women. What additional testing should be done first for them?
c. Of the 9 women tested negative, 3 had had sex with the infected man more than 6 months earlier, 3 had had sex with him between 3 and 6 months earlier, 2 had sex with him about 1 and 3 months earlier, and one had sex with him this morning for the 1st time. What should be done with these women?
d. What confirmatory test should be performed after the positive ELISA results? What would indicate a positive result in this test?
e. What tests indicate how much HIV has infected the patient's immune system?
f. What tests can be used during therapy to determine whether the Anti-virals are working?
g. What tests can be used to determine whether the HIV-infected person is resistant to a certain therapy?