Draw a flowchart to illustrate how a change in a nucleotide in a DNA strand leads to symptoms experienced by those with sickle cell anemia.
Added by Melissa G.
Step 1
This is a mutation in the HBB gene on chromosome 11, where the nucleotide adenine (A) is replaced by thymine (T) in the sixth codon of the beta-globin gene. This codon change from GAG to GTG leads to the substitution of the amino acid valine for glutamic acid in Show more…
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Draw a small concept map (BioSkills 12 ) showing how selection, genetic drift, gene flow, and mutation relate to genetic variation.
Draw out an SRF model of the sickle-cell disease. Include the beta-globin gene, nucleotide sequence, allele, hemoglobin protein, normal/sickled red blood cells as structures. Make the structures specific to the system. Your model should show how variation at the genetic level results in phenotypic variation. Therefore, you should have more than 1 box with a phenotype to show this variation. If your genotype is homozygous for the sickle cell allele, what type(s) of red blood cells will you have? ["True" or "False"] Sickled red blood cells ["True" or "False"] Normal red blood cells
Josee P.
Assertion: Sickle cell anaemia is an example of point mutation. Reason: It occur due change in single nucleotide in beta gene.
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