00:01
In order to answer this question, let's talk about dna replication.
00:04
It says draw or label a diagram of a dna molecule undergoing replication and describe the process of replication in both the leading and lagging strand.
00:12
You should know that what a replication bubble looks like, including a directionality, and be able to identify the various enzymes and other molecules using this process.
00:21
And well, there you have all the enzymes proteins that they want you to state.
00:27
So let's draw our parental dna stand.
00:33
It is a double standard molecule, remember? so this is going to be the 3n and this is the 5th.
00:43
So remember that one property of the dna molecule is that one is that both strands are ant -parallel, it means one strand goes from 3 to 5, the second strand goes from 5 to 3.
00:58
So, the enzyme that is going to open your strand, because your strand is a double -estranded molecule, but you have to open and produce a replication bubble like this.
01:08
Okay? the enzyme responsible for that is called dna helicase.
01:15
The helicase is going to open your double -standed molecule, and you're going to have here some proteins that are going to keep this replication bubble like this, so they don't collapse again.
01:28
Okay? so these proteins are called single stranded bubble, i'm sorry, binding protein.
01:33
Okay, single strand of binding protein.
01:36
So this is it.
01:37
Now, each of these two parental strands have to synthesize a daughter strand.
01:43
Okay, and the enzyme responsible for synthesizing or for polymerizing that new strand is called dna polymerase three.
01:52
And this dna polymerase three synthesizes dna only in the five to three and also this dna 3 cannot start synthesizing out of nothing.
02:01
It requires a short segment of rna.
02:04
And this short segment of rna is going to be like this.
02:08
And it's called a primary.
02:10
And this primary is placed by the enzyme primates.
02:15
Okay.
02:15
So once you have your primer here, your dna polymer is going to be able to come in extra polymerizing your dna molecule.
02:23
So as this strand goes from 3 to 5, then this strand is going to go from 5 to 3.
02:29
5 and 3...