Endochondral ossification begins with the formation of (A) a fibrous connective-tissue model. (B) a cartilage model. (C) an osseous model. (D) a calcified model. (E) no model at all, just the presence of osteoblasts.
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This is a type of bone development that primarily occurs in long bones. Show more…
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In endochondral bone formation (a) osteoclasts produce bone (b) joints connect fibers (c) the skeleton consists of cartilage (d) bones develop from cartilage templates (e) bones form in noncartilage connective tissue.
1. In the formation of bones in utero (as a fetus, before the child is born): a. Endochondral ossification forms most bones of the body by replacing a hyaline cartilage model with bone. b. Intramembranous ossification forms the bones of the cranium first. Then, after the child is born, endochondral ossification will occur, forming the other bones of the body. c. Intramembranous ossification forms the skull cap bones by replacing hyaline cartilage with bone. d. None of the statements are true about the formation of bones in utero. e. Compact bone is first formed, then remodeled into cancellous bone where needed. 2. Bone, cartilage, tendons/ligaments are all types of connective tissue and share some of the same molecules within each of their matrices. Cartilage acts as a good shock-absorber, whereas bone and tendons/ligaments are not. Which molecule is found at high amounts within the matrix of cartilage, allowing it to have a low-friction surface and act as a good shock-absorber? a. Calcium b. Chondrocytes c. Proteoglycans d. Elastin e. Collagen 3. Which type of bone, based on histology, is found primarily at the outer part of the diaphysis of a long bone but does not form the majority of the epiphysis of the long bone? a. Endosteum b. Periosteum c. Bone marrow d. Cancellous e. Compact
Sri K.
STEPS FOR ENDOCHONDRAL OSSIFICATION - Put these events in order by cutting them out and moving them around. 1. Embryonic mesenchymal (stem) cells cluster at a region and differentiate into chondroblasts. 2. Chondroblasts secrete hyaline cartilage matrix. 3. Chondroblasts become chondrocytes as they become trapped in their cartilage matrix. 4. Clusters of cartilage-building areas fuse to form the cartilage model of bone. 5. Osteoblasts move into the cartilage model and begin replacing the chondrocytes. 6. Osteoblasts begin to secrete collagen as the extracellular matrix (ECM) of bone. 7. Calcification occurs as calcium and minerals harden the ECM into bone. 8. Blood vessels grow into spaces between trabeculae. 9. Gradually, the individual clusters fuse, forming trabeculae. 10. Osteoblasts become osteocytes as they become trapped in their own ECM. 11. Mesenchymal stem cells condense on the periphery, forming the periosteum.
Madhur L.
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