Explain why it is very important to determine the blood group of both donor and recipient before giving a blood transfusion. (6) Natalie (A, Rh-) has a daughter Maria (O, Rh+). Angel (AB+), Dwayne (O-) and Vang (B+) all claim to be Maria’s father. Who is telling the truth? Justify your answer.
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1. A person of blood type B needs urgent blood transfusion. Which blood groups are acceptable and which are not? What is the basis of your choice? 2. Could a brother's sister blood be transfused to him without typing if the parents are of the following blood types: A. Both AB B. B and O C. Both O? Explain. 3. A woman learns that her fiancé was the fifth child in a family in which the second and fourth were born with erythroblastosis fetalis. She is told that it is impossible for her to have an affected child and asks if this is true or not. What should your answer be? Justify. 4. Assume that the Rh factor is an autosomal dominant trait. Assume further a case of disputed paternity involving woman X, two men Y and Z, and four children: A, B, C, and D. On the basis of blood properties, assign each child to his father whenever possible.
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Check Your Understanding An expectant mother has type B blood, and her genotype is I^B i; the father has type A blood, and his genotype is I^A i. What are the potential genotypes and phenotypes of the blood types of their offspring? If a father has type A blood (genotype I^A I^A) and the mother has type O blood (genotype ii), what are the potential genotypes and phenotypes of the blood types of the offspring? How can blood type be used to establish the identity of an individual in a paternity suit? Can it be used as the only evidence of paternity? What is the potential danger from receiving the wrong type of blood during a transfusion? Why? A patient who is waiting on a kidney transplant list gets notification that there may possibly be a kidney from another transplant center near the patient's home. The patient has type A blood. What blood type(s) do the transplant coordinators need to consider for this patient? (Circle the correct answer.) a. A only b. AB only c. O only d. A and O e. B If a mother has type O blood, and the father has type B blood, what are the potential blood types of their offspring? Recently Mary underwent extensive surgery and needs a transfusion. She has type A blood. Her friend Paul has type AB blood, and another friend, Thomas, has type O blood. Which of her friends' blood can be safely transfused? Why? Chapter 13 | It's All in the Genes Understanding Basic Mendelian Genetics
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Could a man with an AB blood type be the father of an O child? Could a man with an O blood type be the father of an AB child? Could a Type B child with a Type A mother have a Type A father? What are the possible genetic combinations of an offspring when the blood types of one parent is A and the other is B? Rh Blood Group Suppose the Victim marries Suspect #2. What are the chances for an Rh+ child? An Rh- child? Explain how erythroblastosis fetalis may develop. Under what conditions might a person with Rh- blood develop Rh agglutinins? Why can Rh+ blood be given only once to a non-sensitized person who is Rh-? What is likely to happen to a donor's cells if an Rh- person who is sensitive to Rh+ blood receives a transfusion of Rh+ blood? Others What blood type is most common in U.S. citizens? What blood type was considered the universal donor? Explain. What blood type was considered the universal recipient? Explain.
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