Question

For each different mutant cell described below, assume that ONE nucleotide has been mutated in the sequence so that the protein's function has changed. Name as many single nucleotide changes that could result in the description. Cell 2: Many different types of proteins are too short but have the correct sequence up to the point which the amino acid sequence just stops. Insertion mutation that creates longer amino acid chains Nonsense Mutation caused by the creation of a new stop codon. Silent mutation that changes the codons but not the amino acids Missense mutation caused by a different amino acid than the original version

          For each different mutant cell described below, assume that ONE nucleotide has been mutated in the sequence so that the protein's function has changed. Name as many single nucleotide changes that could result in the description.
Cell 2: Many different types of proteins are too short but have the correct sequence up to the point which the amino acid sequence just stops.
Insertion mutation that creates longer amino acid chains
Nonsense Mutation caused by the creation of a new stop codon.
Silent mutation that changes the codons but not the amino acids
Missense mutation caused by a different amino acid than the original version

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For each different mutant cell described below, assume that ONE nucleotide has been mutated in the sequence so that the protein's function has changed. Name as many single nucleotide changes that could result in the description.
Cell 2: Many different types of proteins are too short but have the correct sequence up to the point which the amino acid sequence just stops.
Insertion mutation that creates longer amino acid chains
Nonsense Mutation caused by the creation of a new stop codon.
Silent mutation that changes the codons but not the amino acids
Missense mutation caused by a different amino acid than the original version

Added by Hugo M.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

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Solved by Expert Farhan Anwar

02/26/2022

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For each different mutant cell described below, assume that ONE nucleotide has been mutated in the sequence so that the protein's function has changed. Name as many single nucleotide changes that could result in the description. Cell 2: Many different types of proteins are too short but have the correct sequence up to the point which the amino acid sequence just stops. Insertion mutation that creates longer amino acid chains Nonsense Mutation caused by the creation of a new stop codon. Silent mutation that changes the codons but not the amino acids Missense mutation caused by a different amino acid than the original version

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Transcript

00:01 Okay, so this question is asking about what kind of mutation cell 2 is.

00:11 So cell 2, so many different types of proteins are too short, but have the correct sequence up to that point, meaning that there is a sequence of normally what should be.

00:33 So amino acid 1, amino acid 2, amino acid 3, 1, 2, 3, amino acid 4, amino acid 5, and amino acid 6, let's say.

00:59 So these proteins are okay up to this point, let's say.

01:07 So they make amino acid 1, amino acid 2, and amino acid 3.

01:13 Everything up to there is correct.

01:18 It is exactly as it should be.

01:20 It just doesn't go any further.

01:22 So what probably has happened is this, as highlighted, a nonsense mutation caused by the creation of a new stop codon.

01:33 So instead of whatever amino acid for us, let's say that there's a mutation.

01:41 A mutation that has put in, a stop.

01:48 This is there even if immune acid 5 and immune acid 6, even if the codon is still present, the ribosome is not going to go beyond the stop.

01:59 Right? so this is going to end right there.

02:03 So it is always going to make shorter sequences.

02:08 This is a nonsense mutation.

02:11 Okay.

02:12 Nonsense mutation.

02:13 Nonsense because it does not go beyond the stop.

02:21 It's not an insertion...

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