Fructose-6-phosphate is phosphorylated to fructose-(1-6)-bisphosphate as part of the glycolytic pathway. The phosphorylation of fructose-6-phosphate by phosphate is described by the following equation: Fructose-6-phosphate + Pi ? Fructose-(1-6)-bisphosphate ?G0' = +47.7 kJ/mol Suppose that the phosphorylation of fructose-6-phosphate is coupled to the hydrolysis of ATP (-30.5 kJ/mol). What is the ?G0' for the coupled reaction?
Added by Antonio H.
Close
Step 1
5 kJ/mol) to the energy required for the phosphorylation of fructose-6-phosphate (47.7 kJ/mol). ** Show more…
Show all steps
Your feedback will help us improve your experience
Joseph Sotelo and 78 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
The reaction for the isomerization of glucose 6-phosphate to fructose 6-bisphosphate is catalyzed by the enzyme phosphoglucose isomerase and has a standard free energy change of ΔG°' = 1.7 kJ/mol. If the cellular concentration of glucose 6-phosphate is 7.7 mM and the concentration of fructose 6-phosphate is 3.98 mM, what is the ΔG of the reaction at 37°C? The gas constant R = 8.314 J/(mol·K).
Adi S.
The equilibrium reaction of glucose-6-phosphate to fructose-6-phosphate has a Gibbs free energy of 4 KJ/mol. Explain the meaning of this statement? How does this reaction occur in the glycolytic pathway?
One step in the gluconeogenesis pathway for the biosynthesis of glucose is the partial reduction of 3 -phosphoglycerate to give glyceraldehyde 3 -phosphate. The process occurs by phosphorylation with ATP to give 1,3 -bisphosphoglycerate, reaction with a thiol group on the enzyme to give an enzymebound thioester, and reduction with NADH. Suggest mechanisms for all three reactions.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD