Imagine that neurotransmitter binding results in a depolarization of the postsynaptic cell. This is known as an EPSP. IPSP. EPSP or IPSP depending on the type of neuron involved. EPSP or IPSP depending on type of neurotransmitter involved.
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On the other hand, an IPSP (inhibitory postsynaptic potential) is a hyperpolarization of the postsynaptic cell, making it less likely to generate an action potential. In this case, we are given that neurotransmitter binding results in a depolarization of the Show more…
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Adi S.
In the neuromuscular junction, the stimulation of the motor neuron ultimately results in the release of the neurotransmitter acetylcholine from the presynaptic neuron into the synapse. The release of acetylcholine into the synapse is dependent on the activation of synaptotagmin, which is required for the fusion of acetylcholine-containing vesicles to the plasma membrane. Next, acetylcholine enters the synapse and binds to and activates the transmitter-gated ion channel on the muscle cell, initiating membrane depolarization and muscle contraction.
Post-synaptic potentials are either excitatory (EPSP) or inhibitory (IPSP). Describe how these excitatory or inhibitory effects are determined by the actions of neurotransmitters at post-synaptic receptors. That is, describe the changes to the post-synaptic neuron brought about by the actions of the particular neurotransmitter(s). To answer this question fully, consider (and explain) the roles of transmitter-dependent ion channels and type of receptor (ionotropic or metabotropic).
Sri K.
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