Access the Mouse Party interactive module. Select one mouse, influenced by the drug of your choice, and complete the simulation by viewing all of the relevant slides. Next, perform a web search on the drug you selected and locate additional resources that will help you answer the following: Briefly describe why you chose this drug and how many people are estimated to be using/abusing it. Explain how the drug influences both the brain and behavior. Discuss what you think (if anything) needs to be done to combat addiction to this substance and provide a rationale for your position.
Added by Teresa D.
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Choose a drug: I chose **Cocaine**. Show more…
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Choose an illicit drug and explain the pharmacology of its action at a synapse.
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You are a technician in a biochemistry lab running receptor binding experiments. The target membrane-bound receptor has been partially purified from mouse, rat, and human cell lines. Using the same radioactive ligand in a saturation binding assay for each species' receptor, you generate the binding data in the table. The dependent variable, Y, is the fraction of binding sites occupied by the ligand. Ligand concentration (nM) | Y for mouse receptor | Y for rat receptor | Y for human receptor 0.20 | 0.048 | 0.29 | 0.17 0.50 | 0.11 | 0.50 | 0.33 1.0 | 0.20 | 0.67 | 0.50 4.0 | 0.50 | 0.89 | 0.80 10 | 0.71 | 0.95 | 0.91 20 | 0.83 | 0.97 | 0.95 50 | 0.93 | 0.99 | 0.98 Determine the Kd for the human receptor in this binding experiment. human receptor Kd = nM Which receptor binds most tightly to this ligand?
Md.Daniyal A.
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