00:01
Hello students, in this video we will discuss about chromosomal and or dna abnormalities of following tumors.
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First is follicle center lymphoma.
00:35
The most common chromosomal abnormalities in follicular center lymphoma is that t1418 q32 -q21 translocation which results in the over expression of the pcl2 gene.
01:14
Other chromosomal abnormalities that can be seen in follicular center lymphoma include gains of chromosomes 7, 12 and 18 and losses of chromosomes 6, 13 and 17.
01:42
Dna mutations that can be seen include pcl2, myc, ezh2 and foxo1 genes.
02:10
Next mental cell lymphoma.
02:19
The most common chromosomal abnormality in mental cell lymphoma is the t1114 q13 -q32 translocation which results in the over expression of the cyclin t1 gene.
03:07
Other chromosomal abnormalities that can be seen in mental cell lymphoma include gains of chromosomes 7, 12 and 18 and losses of chromosomes 6, 13 and 17...