Methylation of a CpG motif inhibits gene transcription by a. Physically blocking RNA polymerases b. Attracting histone deacetylases (HDAC) molecules, which reconfigure the chromatin c. Increasing the rate of mutation at the site d. All of the above e. None of the above
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Methylation of a CpG motif does not physically block RNA polymerases, but it can affect the binding of transcription factors. b. Methylation of a CpG motif can attract histone deacetylases (HDAC) molecules, which reconfigure the chromatin and make it less Show more…
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