Question

MicroRNAs are small RNA molecules that bind to the 3′ end of mRNA and suppress translation . Some eukaryotic mRNAs have internal ribosome-binding sites downstream of the 5′ cap, where ribosomes normally bind. In one investigation, miRNAs did not suppress translation by ribosomes that had attached to internal ribosomebinding sites (R. S. Pillai et al. 2005. Science 309:1573–1576). What does this finding suggest about how miRNAs suppress translation?

Name: micrornas are small rna molecules that bind to the 3 end of mrna and suppress translation some eukaryotic mrnas have internal ribosome binding sites downstream of the 5 cap where ribosomes n 17455
Uploaded: 2023-01-13T20:49:43-08:00
Duration: 2 min 15 s
Channel: Sri K
Description: micrornas are small rna molecules that bind to the 3 end of mrna and suppress translation some eukaryotic mrnas have internal ribosome binding sites downstream of the 5 cap where ribosomes n 17455

          MicroRNAs are small RNA molecules that bind to the 3′ end of mRNA and suppress translation . Some eukaryotic mRNAs have internal ribosome-binding sites downstream of the 5′ cap, where ribosomes normally bind. In one investigation, miRNAs did not suppress translation by ribosomes that had attached to internal ribosomebinding sites (R. S. Pillai et al. 2005. Science 309:1573–1576). What does this finding suggest about how miRNAs suppress translation?

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Biology for AP Courses

Julianne Zedalis, John Eggebrecht

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MicroRNAs are small RNA molecules that bind to the 3′ end of mRNA and suppress translation . Some eukaryotic mRNAs have internal ribosome-binding sites downstream of the 5′ cap, where ribosomes normally bind. In one investigation, miRNAs did not suppress translation by ribosomes that had attached to internal ribosomebinding sites (R. S. Pillai et al. 2005. Science 309:1573–1576). What does this finding suggest about how miRNAs suppress translation?