Modifications to chromatin can affect transcriptional activity by changing the accessibility of DNA to the transcription machinery. The given descriptions are examples of various processes that may or may not cause remodeling of chromatin. Match each description to the effect it has on transcriptional activity caused by chromatin remodeling. a. Activates b. Inactivates c. Activates and inactivates d. No effect 1. Histone methylation occurs at different amino acids. 2. A transcription factor binds an enhancer sequence. 3. Histone acetyltransferases attach acetyl groups to the N-terminus of histones. 4. Histone deacetylases remove acetyl groups from the N-terminus of histones.
Added by Steven S.
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Histone methylation occurs at different amino acids: Methylation can either activate or inactivate transcription depending on the specific amino acid and the context. So, the answer is (c) Activates and inactivates. Show more…
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