Part A
If the anterior pituitary is responsible for hyperthyroidism,
the level of TSH will be reduced along with the levels of
T3 and T4, which are the thyroid hormones; the level of TRH from
the hypothalamus will be elevated.
Part B
In a nonfunctioning adenoma of the corticotrophs, which are the
cells that secrete ACTH, the CRH level will be reduced, and the
cortisol level will be reduced.
Part C
Cushing’s disease is caused by a pituitary adenoma, resulting in
an increase in blood cortisol; Cushing’s syndrome is an elevated
cortisol level as the result of some other cause. If a patient has
an elevated cortisol level and they are found to have a tumor of
the adrenal cortex, the condition would be diagnosed as Cushing’s syndrome.