Please help.
1. Provide the requested information. Pay close attention to stereochemical details when necessary.
1. Camphorsulfonic acid (catalyst)
Me
THF
2. NaH, DMSO
(single enantiomer)
Reagents that can carry out this transformation.
Product after these transformations.
1. Pd-BaSO4, EtOH then w/u
HCl
HO, MeOH
A
2. NaOMe, MeOH then w/u
Then workup
Tricycle
Product after these transformations.
Product after these transformations.
HBr
1) NaCN, DMSO then workup
2a) DIBAL-H (1 equiv.) -20
HOCHCHOH
MeCN then workup
b) HOAc, NaOAc then workup
B
Product after these transformations.
Me3Si 1 MgBr, THF, 0C then workup
B 2 PCC, acetone -20C then workup
c
Product after these transformations.