Score: 286/450 Most mechanisms of gene expression regulation work at the level of _____ translation transcription translocation replication Question Value: 15
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Step 1: Gene expression regulation is the process of controlling which genes are expressed and at what level. Show more…
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Section 1: Multiple choice (0.25 point each/1 points total): Enhancers are __________. A. operator sequences that repress transcription by blocking RNA polymerase initiation B. binding sites for general transcription factors C. promoter-proximal regulatory sequences that recruit TATA-binding protein (TBP) D. binding sites for catabolite activating protein (CAP) E. regulatory sequences that activate transcription from distant cis-linked promoters Intrinsic transcriptional termination __________. A. stimulates transcriptional initiation B. results from phosphorylation changes in the C-terminal tail of the RNA polymerase II C. occurs in eukaryotes and depends on AAUAAA sequences in the mRNA 3’-UTR D. occurs in prokaryotes and depends on hairpins that form in the mRNA 3’-UTR E. depends on rho factor Dosage compensation is necessary because __________. A. some regions of the genome contain more genes than others B. genes near heterochromatin tend to be silenced through position effects C. enhancers can activate transcription whether they are upstream or downstream of a gene D. genes on the X chromosome are present in twice as many copies in females than in males E. The Y chromosome does not contain many protein coding genes The process of transcriptional attenuation that regulates E. coli trp operon expression is an example of a prokaryotic-specific regulatory mechanism because __________. A. translation initiates while transcription is occurring in prokaryotes B. eukaryotic genes are not regulated by operator sequences C. allosteric changes in transcription factors do not occur in eukaryotes D. tryptophan is not required in eukaryotic cells E. transcriptional enhancers make attenuation unnecessary
Suman K.
1) Which level of gene expression is most regulated in prokaryotes? a) Transcription b) Post-translational modification c) Translation d) RNA processing 2) Which of the following are found in the lac operon sequence? a) lac Z gene b) lac Y gene c) lac I gene d) lac promoter e) operator sequence 3) Which of the following statements about B-galactosidase is true? a) B-galactosidase is produced when lactose is present b) B-galactosidase creates allolactose from glucose c) B-galactosidase cleaves lactose into galactose and glucose d) B-galactosidase is made from the lac Y gene 4) The lac operon will only be transcribed if glucose is absent. True False 5) The lac repressor... a) blocks B-galactosidase from binding to the promoter b) is always made c) is inactivated by allolactose d) binds to the lac operator sequence 6) Which of the following determines if the lac repressor blocks RNA polymerase? a) The presence of sucrose b) The presence of glucose c) The presence of maltose d) The presence of lactose 7) cAMP... a) helps increase transcription of the lac operon b) is made if glucose is present c) is made if glucose is absent d) binds to CAP protein 8) Which of the following would prevent transcription of the lac operon? a) Neither glucose nor lactose are present b) Lactose is present, but glucose is not c) Glucose and lactose are present d) Glucose is present, but lactose is not 9) Which of the following must be true when lactose is absent but glucose is present? a) The lac repressor is bound to allolactose b) B-galactosidase is produced c) cAMP is made d) The lac repressor is bound to the operator e) RNA polymerase is bound to the promoter 10) Which of the following must be true when lactose and glucose are present? a) The lac repressor is bound to the operator b) cAMP is made c) The lac repressor is bound to allolactose d) RNA polymerase is bound to the promoter e) B-galactosidase is produced 11) miRNAs... a) can lead to blockage of translation for an mRNA b) can lead to destruction of an mRNA c) are made by dicer chopping up a large stretch of dsRNA to form smaller stretches of dsRNA d) block mRNAs from their own genes 12) Nucleosomes contain a) H1 linker b) histone octamer c) DNA Polymerase d) RNA e) histone hexamer f) DNA 13) Control elements include... a) promoters b) proximal control elements c) transcription factors d) enhancers e) RNA polymerase 14) Acetylation of histones leads to a) a more open structure of chromatin b) decreased transcription c) increased transcription d) a more closed structure of chromatin 15) Which of the following help to regulate gene expression in eukaryotes by affecting whether or not transcription may occur? a) transcription factors b) siRNA c) enhancers d) DNA methylation e) histone acetylation 16) Which of the following help to regulate gene expression in eukaryotes by directly affecting whether or not translation may occur? a) siRNA b) histone acetylation c) transcription factors d) enhancers e) DNA methylation
Josee P.
In order to prevent a regulatory protein from affecting gene expression you would need to block physical contact between that protein and: DNA mRNA ribosomes RNA polymerase Which of the following mutations could convert a proto-oncogene into an oncogene? A deletion of most of the proto-oncogene coding sequence A mutation that blocks transcription of the proto-oncogene A mutation that creates unstable proto-oncogene mRNA A mutation that leads to a significant increase in the amount of the proto-oncogene protein product Which of the following statements regarding the lac and trp operons is true? Both the lac and trp operon repressor proteins are constantly produced in bacterial cells The lac operon repressor protein is always produced, but the trp operon repressor protein is only made when trp is absent The lac operon repressor protein is always produced, but the trp operon repressor protein is only make when trp is present The lac operon repressor protein is made only when lactose is present, but the trp repressor protein is made all the time Which of the following are two mechanisms used by eukaryotic cells to regulate transcription? DNA acetylation and DNA methylation DNA amplification and histone methylation DNA methylation and histone acetylation DNA methylation and histone amplification
Sri K.
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