Select all answers that are TRUE about glutamine synthetase effectors:
A. Glutamine, the end product of the reaction, binds to glutamine synthetase and inhibits its activity.
B. A high concentration of ammonia activates uridylylation of the regulatory protein PII.
C. Deuridylylated regulatory protein PII reverts the glutamine synthetase activity towards the synthesis of glutamate from glutamine.
D. Glutamine, the end product of the reaction, inhibits uridylylation of the regulatory protein PII.
E. Glutamine synthetase is activated by adenynylation from ATP.
F. Uridylylated regulatory protein PII activates glutamine synthetase by deadenylylation of the enzyme.