Select the true statements regarding antibody (specifically, immunoglobulin G) structure. The antigen-binding site is located in the Fc fragment. Both the Fab and Fc fragments contain constant domains. The heavy and light chains are linked by noncovalent and disulfide bonds. Both the Fab and Fc fragments have variable domains. The antigen-binding site is formed as a combination of variable domains from one heavy and one light chain.
Added by Miranda W.
Close
Step 1
Step 1: Both the Fab and Fc fragments have variable domains. Show more…
Show all steps
Your feedback will help us improve your experience
Shyam P and 58 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Which of the following statements regarding Immunoglobulins is FALSE? The constant regions determine the "class" of the antibody. Immunoglobulin G consists of four polypeptide chains and has secondary and tertiary protein structure. Polypeptide chains in immunoglobulins are held together by disulfide bonds. The two antigen-binding sites on an immunoglobulin allow binding to two different epitopes on antigens. The variable region determines the shape of the antigen-binding site.
Shaiju T.
What statement about antibodies is FALSE? A. Antibodies are composed of 2 heavy chains and 2 light chains. B. Disulfide bonds link the heavy and light chains together. C. An F(ab')2 fragment would elute before an Fab fragment (aka - have a shorter retention time) on a size exclusion column. D. A monomeric antibody can bind to only one antigenic determinant at a time. E. The hinge region of antibodies improves the efficiency of antigen binding.
Sri K.
Which of the following statements is true? (A) An antibody has one antigen-binding site. (B) A lymphocyte has receptors for a single antigen. (C) Every antigen has a single epitope. (D) A liver or muscle cell makes two classes of MHC molecule.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD