Sickle cell anemia is a genetic condition that occurs because of a single point mutation in the DNA gene for hemoglobin. How is this mutation expressed in humans?
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Sickle cell anemia is caused by a single point mutation in the gene that codes for the beta-globin chain of hemoglobin. This mutation occurs in the HBB gene located on chromosome 11. Show more…
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Many different types of mutations can occur within the body. Sickle cell anemia is a disease that occurs when a mutation in the base pair of the hemoglobin beta gene causes a single replacement of the amino acid glutamic acid by the amino acid valine. As a result of this mutation, the individual's blood cells take on a sickle shape under certain conditions. Which type of mutation causes sickle cell anemia?
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Alleles for Sickle Cell Anemia occur at higher rates in some populations compared to others. Here, please explain what Sickle Cell Anemia is, how it is inherited, and why in spite of any negative side effects has it persisted as a trait among humans. Be as detailed as possible. You may even include a punnet square in your answer.
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