Somatic cell nuclear transfer: (select all answers that apply): a) was pioneered by Shinya Yamanaka b) is a technique that de-differentiates cells via the expression of just four transcription factors (Klf4, Oct4, Sox2, and c-Myc) c) was the basic approach used to clone "Dolly the sheep" d) involves the fusion of a somatic cell with an ES cell e) was first demonstrated by transferring a mouse fibroblast nucleus into an enucleated Xenopus oocyte
Added by Juan Jos- M.
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So, this option is incorrect. b) This statement refers to the process of creating induced pluripotent stem cells (iPSCs) by introducing the four transcription factors (Klf4, Oct4, Sox2, and c-Myc) into a somatic cell. This is not related to somatic cell nuclear Show more…
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Madhur L.
Which of the following statements is true regarding somatic cell nuclear transfer (SCNT) experiments? Choose one option below. a. They established that some genes are gradually lost as the cells differentiate into specialized tissues. b. They confirmed that a somatic cell has all the genetic information necessary to make any other cell type in the body. c. The highest efficiency of SCNT was achieved when nuclei from permanently differentiated cells (rather than early embryonic cells) were fused with the enucleated eggs.
Luke H.
Somatic cell nuclear transfer is one technique used to make cells in the labs that develop into embryos that are clones, that are then placed into the uterus of a surrogate mother to grow. This process includes the following steps: a. Removing the nucleus of a egg cell and of an egg cell, then transfer the egg cell nucleus into the somatic cell. b. Removing the nucleus of a sperm cell and of an egg cell, then transfer the sperm cell nucleus into the egg cell. c. Removing the nucleus of a somatic cell and of an egg cell, then transfer the somatic cell nucleus into the egg cell. d. None of the above
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