00:01
Hello everyone, in this question we have been asked that the f1 subunit of the atp synthase.
00:08
So f1 here is composed of three copies of each of subunits alpha, beta and one each of subunits of gamma, delta and epsilon.
00:22
The f1 portion of atp synthase is hydrophilic and it is responsible for hydrolyzing the atp.
00:35
The f1 subunit protrudes into the mitochondrial matrix space subunits alpha and beta make a hexamer with six binding sites, three of them are catalytically inactive and they bind the adp.
00:48
So therefore here our right answer will be option d that it binds the piadp and the atp and due to the 120 degree rotation of gamma subunit there is change in the beta subunit due to which this binding and release takes place.
01:07
Then in the question 2 it says that in the electron transport chain an inhibitor of complex 2 would be.
01:13
So complex 2 is basically the succinate dehydrogenase which passes on the electron to the coenzyme q that is the complex 3.
01:25
So here not accumulated here it is basically the electrons from fadh2 that passes on from the complex 2.
01:33
Then option 3 says that still allow the consumption of nadh by electron transport chain.
01:41
So this here will be correct.
01:43
The electron transport chain will not be shut down because the nadh electron transport is still taking place.
01:49
So therefore here our right answer is option c.
01:55
Then in the next question it says that f0 domain that is the subunit of atp synthase binds directly to the f0 part bound to the inner mitochondrial membrane is involved in the proton translocation.
02:12
It is a proton pore that is embedded in the mitochondrial membrane and it consists of 3 main subunits a, b and c.
02:23
The 6 c subunits make up the rotor ring and subunits b make up a stalk connecting to f1 subunit.
02:30
So here our right answer will be option b that is it functions as a highly controlled proton channel.
02:38
Then in the next question it says that which metabolic reaction is involved with carrying the electrons from the cytosol to the matrix.
02:47
So here option a says oxidation of cytochrome c by complex 4.
02:53
So the complex 4 here is cytochrome c oxidase and it is oxidized by the passage of the electron.
03:02
So here the cytosol and matrix is not involved and it passes the proton from the matrix to the inner mitochondrial space.
03:10
So this is not correct.
03:12
Then in the option b malate aspartate shuttles.
03:15
So in this basically the cytosol and the matrix is involved.
03:21
Then option c says oxidation of qhd by complex 3 which is coenzyme q cytochrome c reductase.
03:28
So in this also the matrix and inner mitochondrial membrane space is involved.
03:35
Then option d says oxidation of succinate to mat fumerate.
03:39
So that takes place in only the mitochondrial matrix.
03:43
Then option e says oxidation of cytochrome c.
03:46
So that takes place in the inner mitochondrial membrane...