The drug in ______ form is more permeable to the membrane for drug absorption. ______ form of a drug is less water-soluble. A Unionized, Ionized B Ionized, Unionized C Unionized, Unionized D Ionized, Ionized
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" Drug absorption across biological membranes (which are lipid bilayers) is generally favored by the un-ionized (unionized) form of the drug. This is because the unionized form is more lipid-soluble and can more easily pass through the lipid membrane. The ionized Show more…
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Drugs that are predominantly unionized (uncharged) at physiological pH (7.4) will have more extensive distribution when compared to drugs that are ionized (charged).
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