The following amino acid sequence is found within the protein coding region of a gene: Met-Ser-Pro-Trp-His-Ala In a mutant, the amino acid sequence was altered to: Met-Ser-Pro-Gly-His-Ala What kind of mutation most likely occurred in the DNA? Missense Frameshift Silent There is not enough information to answer this question Nonsense Question 24 __________ mutations produce new activities and are usually dominant. Forward Gain of function Induced Reverse Auxotrophic
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A gene encodes a protein with the following amino acid sequence: $$\mathrm{Met-Trp-His-Arg-Ala-Ser-Phe}$$ A mutation occurs in the gene. The mutant protein has the following amino acid sequence: $$\mathrm{Met-Trp-His-Ser-Ala-Ser-Phe}$$ An intragenic suppressor mutation restores the amino acid sequence to that of the original protein: $$\mathrm{Met-Trp-His-Arg-Ala-Ser-Phe}$$ Give at least one example of base changes that could produce the original mutation and the intragenic suppressor. (Consult the genetic code in Figure 15.10.)
You discover a mutation consisting of a two base insertion in the front half of a gene you are studying. The amino acid sequence after the insertion of the protein expressed from the mutant gene is completely different when compared to the amino acid sequence expressed from the un-mutated version of the gene. The mutation is most likely a/an: Frame-shift mutation Missense mutation Silent mutation Nonsense mutations
Madhur L.
Some mutations which occur in the coding sequence of a gene, have no effect on the resulting amino acid sequence of the protein the gene encodes. This would be an example of a mutation and highlights that the genetic code is missense; degenerate silent; degenerate frameshift; duplicated missense; repeated
Anand J.
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