00:01
Okay, in order to answer this question, let's talk about parachines high signaling.
00:03
Parachrine signaling is when you secrete a molecule or when a cell secretes a molecule, and these molecules are going to act on cells that are nearby, okay, that are very close to the cell that has secreted this molecule here.
00:14
This is paracrine signaling, okay? this is different from endocrine signaling, where this molecule is going to act on cells that are very far away from this cell that produced this molecule here.
00:26
Okay, and this is also different from autokrine signaling, where this molecule is going to bind to the same, or to receptors on the membrane of the cell that secreted this molecule.
00:38
It means in this our own cell.
00:41
This is why it is called autokane.
00:44
So let's look at this question here.
00:47
It says, in a paragon signaling, the signaling molecules affect only, option a is a target cells close to the cell from which it was created, and this is the answer for this question.
00:56
Okay.
00:56
Now let go for question two that is below.
00:58
Are listed the events that occur in a cell to cell communication.
01:02
A signal transduction occurs, plasma memory receptor binds with a ligand, a cellular response is affected, and ligand is released by signaling cell.
01:10
Which of the following list these events in the correct order? so the first step here is going to be option two.
01:19
Remember that the first step of cell to cell communication is the binding of a ligand with its receptor on the cell memory.
01:27
Okay, so this is going to be the first step.
01:29
Then what is going to happen is that, i'm sorry, i did a mistake here because this option forces, ligand is released by signaling cell.
01:41
Okay? this release is like the same as secreted.
01:44
So the ligand is first going to be secreted by a signaling cell.
01:47
So if you have one cell here, for example, this cell here, this cell is going to secrete or it's going to release a signaling molecule here, a ligal.
01:56
Okay? so this is the first step.
01:59
This is the first step.
02:00
Option 4.
02:01
Then you're going to have the second step that is going to be that the plasma membrane the sector binds with a ligand, this step here.
02:08
So this is the second step.
02:11
The third step is going to be this.
02:13
Number one that says signal transduction occurs because once your ligand binds to the receptor, a signal transduction pathway is going to occur.
02:21
Okay, this is the third step.
02:23
And then after this transduction pathway, a biological response is going to occur...