Tolerance to a drug can be explained in terms of both biological adaptaBons to the drug and learned responses to the drug and the environment.
Added by Jerry H.
Step 1
Drug tolerance refers to the phenomenon where an individual requires a higher dose of a drug to achieve the same effect that was previously experienced at a lower dose. Show more…
Show all steps
Your feedback will help us improve your experience
Sana Riaz and 96 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
How can long-term use of one drug (such as aspirin) increase your tolerance to another, different drug (such as alcohol) that you have never encountered?
Sana R.
Which of the following is true of general pharmacodynamic tolerance? It requires the drug to create a functional disturbance, placing homeostatic demand on the organism All effects of the drug are diminished to the same extent because there is reduced bioavailability of drug at target site If upregulation or downregulation of a ligand system occurs, all effects of drug will be diminished Tolerance to a specific effect of the drug may develop independently from other effects of the drug.
Dave K.
Question 50 Which of the following are true of pharmacokinetic (PK) tolerance? A drug produces effects that reduce its own bioavailability through liver enzyme induction The peak effect and duration of action of a drug are increased as a result of this tolerance There is a greater concentration of drug at target site due to increased bioavailability B and C Question 51 The main issue with the depressant vs. stimulant classification is: A drug that is classified as a stimulant can have depressant effects on behavior A drug that is prescribed for depression may also treat anxiety A minor change in the structure of the drug molecule can change its effect All of the above apply
Suman K.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD