A request for 7 units of RBCs for patient Bob Smith. His antibody screen was negative, but 1 of the units was 3+ incompatible at the AHG phase of the crossmatch. Which of the following antibodies may be the cause?
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11- Antibody screening cells are? * Pooled group O and A cells * Any cells that are made up to 3 - 5 % cell suspensions * Cells with a known phenotype, group AB * Prepared group O cell suspensions, each suspension from individual donors. 12- A patient has an anti-c. What type of crossmatch should be performed? * computer" crossmatch. * crossmatch is not required. * An immediate spin crossmatch. * A crossmatch that includes an incubation phase and testing with an anti-human globulin reagent 13- you perform a two unit crossmatch. The screening cells and the donor cells are incompatible in the IAT, but the auto control is negative. What would be the likely cause of this situation? * An antibody to a low frequency antigen in the patients serum * The patient has a positive DAT. * A mixture of antibodies. * An antibody to a high frequency antigen. 14- When a suspected haemolytic transfusion reaction occurs, the first thing to do is? * Check the labels on the bags. * Check the identification of the patient, and the labels on the bags * Administer medication to stop reaction. * Repeat the pretransfusion testing * Stop the transfusion immediately 15- A patient has just arrived by a medical evacuation helicopter to your hospital. On admission, the medical officer collects a specimen and forwards it to the blood bank for group and six unit crossmatch. You perform a ABO and Rh group and you obtain the following results, twice. What is a possible explanation for this group profile? Anti A Anti B Anti AB A1 cells B cells O cells Anti D 4+/0 0 4+/0 0 2+ 3+/0
Adi S.
A 45-year-old man was admitted to the hospital with complaints of extreme fatigue and back pain. The patient was diagnosed with hypertension 8 months ago and was prescribed methyldopa. The patient has never been transfused. Admission testing results are as follows: Hemoglobin: 7.5 g/dL Hematocrit: 22% Total bilirubin: 6.8 mg/dL The attending physician ordered four units of packed red blood cells for transfusion as soon as possible. Records indicate that 3 years ago the patient was transfused with four units of red blood cells following an automobile accident. No serological problems were noted at that time. 5. R's DAT result is interpreted as follows: A. Positive B. Negative C. Positive IgG only D. Positive IgG and C3d E. Positive C3d only 6. Given the patient history and serology results, the next test you would perform would be a(n): A. Elution B. Antibody identification panel C. Autoadsorption D. Warm saline wash technique 7. Which of the following describes the mechanism by which the autoantibody was produced in this case? A. Drug adsorption B. Immune complex C. Membrane modification D. Drug-induced autoimmune hemolytic anemia
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