M, a 48-year-old woman, presented to the physician with a long history of dysfunctional uterine bleeding. She complained of chronic fatigue, headache, and a general malaise. Upon admission to your institution her hemoglobin level was 7.5 mg/dL. She was scheduled for an abdominal hysterectomy the following day and the surgeon requested three units of red cells to be given prior to the surgical procedure. M had no history of transfusion or pregnancy. Forward Typing Reverse Typing Anti-A Anti-B Anti-A,B A1 cells B cells 4+ 0 4+ 1+ 3+ Rh Typing Anti-D D control 3+ 0 Antibody Screen I II III AC IS 2+ 0 2+ 0 37° C 0 0 0 0 AHG 0 0 0 0 Check cells 2+ 2+ 2+ 2+ 4. The serology results best indicate: A. Multiple autoantibodies B. A single autoantibody C. A single alloantibody D. Multiple alloantibodies 5. Which of the following antibodies could be ruled out using the ABO, Rh, and antibody screen? A. Anti-C B. Anti-N C. Anti-Fyb D. Anti-Jka 6. Which of the following antibodies remain after completion of the antibody identification (completion of panel antigram)? A. Anti-S B. Anti-Lub C. Anti-Fya D. Anti-Jkb
Added by Rachel A.
Close
Step 1
The results include forward and reverse typing for ABO blood group, Rh typing, and an antibody screen. Forward typing shows reactions with Anti-A and Anti-A,B, indicating an A blood group. The Rh typing is positive with Anti-D, indicating Rh positive blood. The Show more…
Show all steps
Your feedback will help us improve your experience
Adi S and 80 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Adi S.
An adult woman was brought to the emergency department complaining of abdominal pain, nausea, and vomiting a week after biliary surgery. The recent surgery had been complicated by blood loss requiring 6 units of PRBCs. Before the operation, blood screening showed that the patient's blood type was A (+), with a negative antibody screen. Physical assessments in the emergency department were as follows: - HR: 120 bpm - Temp: 104.6º F - Hgb: 8.9 g/dL (post-op day 7) - Hgb: 6.8 g/dL (post-op day 9) - Hgb: 11.2 g/dL (before discharge from the hospital) - (-) for bleeding on imaging studies of the abdomen and pelvis - Reticulocyte count: 4.2% - Total bilirubin: 2.4 mg/dL - LDL: 593 U/L (reference range: 100-220 U/L) A new type and screen on post-operation day 8 revealed A (+) with a positive antibody screen or indirect antiglobulin test (IAT).
A 60-year-old woman with anemia is admitted to the hospital. Her hematocrit is 17% and she has been experiencing subtle gastrointestinal bleeding over many weeks. Her physician requests 4 units of red blood cells for transfusion. The patient's RBCs are phenotyped as group AB, D-positive. Her antibody screen is negative on the sample drawn in the emergency room, but her records indicate a previously detected anti-E. Only three group AB, D-positive red blood cell units are available in the blood bank's inventory. The blood bank's inventory contains RBC donor units of all ABO and D types. Additional Testing: After antigen screening the 4 units of red blood cells for the E antigen, one of the group AB D-positive units is E-positive.
Supreeta N.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
Watch the video solution with this free unlock.
EMAIL
PASSWORD