00:01
Here for this question, we are looking at an immunoglobulin reaction to an abo mismatch.
00:11
So here, first of all, we're going to be using an igm antibody because these respond well to our abo antigens on the surface of our blood cells.
00:22
So here we have an individual who's a b -type and they are going to be reacting to their a -type cells that they were transfused.
00:29
So here you can imagine we have the red blood cell, whereas in the a type, we'll have the different red blood cell.
00:40
For this abo antigen, they have a base unit for that a or b antigen type, and they're going to have a different sugar presented on the outside.
00:54
So this b individual will have a b -type sugar, and the a individual will have that a -type sugar.
01:01
They specifically named the b -type sugar as galactose, whereas the a sugar is a different type of sugar.
01:11
So here, your igm molecules, which are actually a pentamer, consisting of five antibodies attached together, is going to interact with this a -type sugar and bind to it.
01:27
So in reality, you're going to get a conglomeration of multiple red blood cells that are a -type that are going to be connected together by this five -unit igm molecule...
