What type of Hemolytic Anemia is common with malaria ? Question 2 options: Hereditary Anemia Autoimmune Hemolytic Anemia Acquired Hemolytic Anemia Microangiopathic Hemolytic Anemia
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Malaria is caused by Plasmodium parasites, which infect red blood cells and lead to their destruction. Show more…
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There are other mutations that result in hemolytic anemia. Hemolytic anemia translates to a lack of red blood cells (anemia) due to red blood cells breaking (hemolysis). The red blood cells break open because the abnormal Îł globin sticks together, forming aggregates that cause damage to the red blood cells. The phenotype of hemolytic anemia is dominant, and hemolytic anemia is inherited in an autosomal manner. A list of these mutations is given below. These mutations change only one amino acid and have varying effects on the function of hemoglobin. Mutation Location Change Context of change 1452 G=C TGGCC TGCGC hemolytic anemia 233 C=A GGCC GGACC hemolytic anemia 202 A=G GCAAC GCGAG NORMAL HEMOGLOBIN 1464 G=T TGGTC TGTTC hemolytic anemia A=G TCCAG TCCTG hemolytic anemia A=G AGAAA AGGAA hemolytic anemia
Sri K.
Madhur L.
If intravascular hemolysis is suspected, but hemoglobinemia is not detected visually or spectrophotometrically, the first tests that could be recommended to confirm the suspicion are: a) serum hemopexin b) serum transferrin c) serum haptoglobin d) all of the above In hereditary spherocytosis, MCHC levels are: a) Normal b) Increased c) Decreased d) None of the above In PNH, RBCs are sensitive to: a) complement b) G6PD c) Porphyrin d) None of the above
Md.Daniyal A.
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