Which of the following statements about epigenetic modification is INCORRECT? Select one alternative: Methylation of DNA and histones causes nucleosomes to pack tightly together. Histone acetylation results in the loose packing of nucleosomes. Epigenetic modifications can be passed on to future generations. Epigenetic modification alters the sequence of nucleotides in the DNA.
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Epigenetic modifications are changes to the genome that do not alter the DNA sequence but affect gene expression. Common types of epigenetic modifications include DNA methylation and histone modification. Show more…
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Epigenetic gene regulation is a major topic in regulation of genetic expression, especially over the past several decades of research. Given this topic which of the following is true? a. Epigenetic modification of DNA and histones occurs in both prokaryotes and eukaryotes. b. Methylation of histones typically leads to tighter packing of nucleosomes silencing genes. c. Acetylation of histones typically leads to tighter packing of nucleosomes silencing genes. d. Transcriptionally active DNA is typically tightly packed. e. Epigenetic modification of histones and DNA cannot be transferred to a cell's progeny.
Adi S.
Which of the following statements about epigenetic regulation is false? a. Histone protein charge becomes more positive when acetyl groups are added. b. DNA molecules are modified within CpG islands. c. Methylation of DNA and histones causes nucleosomes to pack tightly together. d. Histone acetylation results in the loose packing of nucleosomes.
DNA methylation has been linked to gene expression. Histone acetylation is a positive charge that is catalyzed by histones, resulting in reduced affinity of the histone and resulting in the formation of open chromatin. Chromatin remodeling leaves DNA open to associate with nucleosomes by repositioning or removing them. One way in which nucleosomes can be modified is by changing their composition, such as histone variants, which can affect nucleosome mobility and positioning.
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