0:00
Hello.
00:02
So the question given here is saying that we have to find out which of the following statement about histone and gene expression is incorrect, right? we have to find which one is incorrect here.
00:15
So statement a, it's saying that stone code is referring to the modification that takes place on the globular domain of the octameric stone core.
00:29
So this is talking about.
00:30
About the histone code that is referring to the modification that takes place on the globular domain of the octomeric histone.
00:38
So this is the correct statement for the histone and the gene expression.
00:43
Right now moving to the next that is saying that on addition of methyl groups to the tail of histone, this will stone protein, this will always result in activation of transcription.
00:58
So they are saying that this will always do this means activation.
01:04
But what we know that addition of methyl group to histone by histone methyl transferases can either activate or further repressed transcription.
01:18
So this depending on the amino acid being methylated and the presence of other methyl or acetyl group in the vicinity.
01:26
Right.
01:26
So this will not always.
01:28
Activate, this can either activate or further repress transcription...