You discover a drug that binds to and antagonizes adenylyl cyclase. You would expect this drug to lead to ____________. A. downregulation of the G protein-coupled receptor (GPCR) B. increased concentration of cAMP in the cytoplasm C. influx of Ca 2+ in the cytoplasm D. activation of protein kinase C (PKC) E. decreased phosphorylation of protein kinase A (PKA)
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If a drug antagonizes adenylyl cyclase, it would inhibit its function, leading to a decrease in the production of cAMP. cAMP is a second messenger that is involved in many biological processes, including the activation of protein kinase A (PKA). PKA is a key Show more…
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