00:01
Okay, so we have this new drug that you're testing, and they find that 30 % of bacteria that have been killed, sorry, that when 30 % of the bacteria have been killed, half the patients will see their numbers will see, oh, sorry, not their numbers, but they'll see a drop in burden.
00:21
In this case, we'll see their infections drop to a level where their immune systems can take care of it, meaning that 30 % mortality of the bacteria, which if we look in the graph, the moraxcella graph, 30 % mortality is roughly, let's say it's under 40.
00:47
We'll just go with 40.
00:49
The effective dose of your drug is going to be 40 millimolar concentration of the drug.
00:58
That's what gets you 30%, or at least a little over 30%.
01:03
In fact, let's actually be a little more specific.
01:10
35 millimolar.
01:13
Actually, let's be even more specific.
01:20
And if you look at the graph, 30 millimolar of the drug gets you 20 % mortality.
01:25
40 millimolar of the drug gets you 35 % of the mortality, right? so, theoretically, well, it's kind of a...
01:54
Theoretically then that your 30 % mortality should be close to actually 37 millimolar...