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CONNECT The development of safe and effective antifungal agents presents a daunting challenge to researchers. Explain. (Hint: Drugs that combat bacterial diseases typically target differences between bacterial cells and those of the host.)
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This means that they share a similar cellular structure, which includes a nucleus that houses their genetic material. This is in contrast to bacteria, which are prokaryotic and do not have a nucleus. In LaTeX format: \textbf{ Show more…
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The development of safe and effective antifungal agents presents a daunting challenge to researchers. Explain. (Hint: Drugs that combat bacterial diseases typically target differences between bacterial cells and those of the host.)
Propose a reason why the development of antiviral drugs is more difficult than developing the antibiotics used to treat bacterial infections.
Medical researchers seek to develop drugs that can kill or restrict the growth of human pathogens yet have few harmful effects on patients. These drugs often work by disrupting the metabolism of the pathogen or by targeting its structural features. Draw and label a phylogenetic tree that includes an ancestral prokaryote and the following groups of organisms: Excavata, SAR clade, Archaeplastida, Unikonta, and, within Unikonta, amoebozoans, animals, choanoflagellates, fungi, and nucleariids. Based on this tree, hypothesize whether it would be most difficult to develop drugs to combat human pathogens that are prokaryotes, protists, animals, or fungi. (You do not need to consider the evolution of drug resistance by the pathogen.)
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