10. Consider the base-catalyzed reaction below:
OH
OH
1) \text{OMe}
2) H$^+
$OMe
A
B
Which of the following reason is correct with regard to the above reaction
a) compound A is a major product because carbon 2 forms a more stable carbocation
b) Compound B is a major product because carbon 1 forms a more stable carbocation
c) compound A is a major product because Carbon 2 is less hindered
d) compound B is a major product because carbon 1 is less hindered
e) choices a) and c) are correct
SECTION B
1) estrogen is a well know contraceptive for family planning, made from estrone which is a natural
mammalian (animal) hormone.
HO
HO
estrone
estrogen
Mg
estrone
A
R$_2$
OH
R$_1$
estogen
OH
a) give structure of compound A
b) give mechanism for the formation of estrogen from compound A and estrone
c) name the reaction on b) above
2. Consider the compounds below
