- Term used to describe an ACh-like effect without distinction as to anatomic site of action.
Added by Jack R.
Step 1
- "ACh-like effect" refers to the effects similar to those produced by acetylcholine (ACh), a neurotransmitter. - "Without distinction as to anatomic site of action" means that the term should describe the effect without specifying where in the body it occurs. Show more…
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The autonomic nervous system (ANS) is widely distributed to and controls the function of the internal organs. The details of that control have largely been elucidated by the use of pharmacological agents that mimic or block the effects of transmitters that are released from the autonomic nerve terminals. i. An agonist is an agent that reacts with a receptor and mimics the action that normally results from the binding of a transmitter to that receptor. Thus, a muscarinic agonist mimics the effects of acetylcholine on a muscarinic receptor. An antagonist blocks the action that normally results from the binding of a transmitter to a particular receptor. Thus, an β-adrenergic antagonist blocks the actions of epinephrine (an β-adrenergic agonist) that normally result from its binding to an β-adrenergic receptor. Assuming that you had an agonist and an antagonist for every autonomic transmitter receptor, how could you determine which receptor types exist in any autonomically controlled effector?
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Using autonomic pharmacological agents, how could you determine which receptors in an organ are subjected to a tonic release of neurotransmitter?
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A drug that affects both divisions of the autonomic system is going to bind to, or block, which type of neurotransmitter receptor? a. nicotinic b. muscarinic c. $\alpha$ -adrenergic d. $\quad \beta$ -adrenergic
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