Pedigree 4 1. What is the most likely mode of inheritance? 2. What is the probability that II-2 is a carrier? 3. What is the probability that II-4 is a carrier? 4. What is the probability that III-3 is a carrier? 5. If III-3 marries a phenotypically normal male, what is the probability that their child would be affected? 6. If III-1 marries a genotypically and phenotypically normal female, what is the probability that their child would be affected? 7. What would be examples of diseases exhibiting this mode of inheritance?
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What is the most likely mode of inheritance? The most likely mode of inheritance is autosomal recessive. Show more…
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The inheritance of an autosomal recessive disease is shown in this pedigree. a. What is the probability that child III-1 is affected with the disease? b. If child III-1 is indeed affected, what is the likelihood that the second child of the couple will be affected as well? c. If child III-1 is phenotypically normal, what is the likelihood that the second child of the couple will be affected?
Madhur L.
8. If individuals IV-3 and IV-4 marry, what is the probability that their first child will have the disease? A. 1/32 B. 1/48 C. 1/64 D. 1/12 E. 1/16 9. Statistically, this trait has a probability of 0.0001 in the population in which these families live. If IV5 is married with a man who is also in this community. What is the probability if your first child has this trait? A. 0.0825% B. 0.0413% C. 0.165% D. 0.123% E. 0.246% 10. If the disease is inherited as an autosomal dominant trait with 50% penetrance, then what would be the possibility that the first child from the marriage of IV3 and IV4 shows this disease? A 1.0 B. 0.0417 C. 0.0313 D. 0.1342 E. None of the answers.
Bryan V.
Questions 3-5. The pedigree illustrates a rare trait controlled by a single gene, gene A. Use this information to answer the questions below. 3. What is the genotype of individual III-4? a) 2/3 AA ; 1/3 Aa b) 1/3 AA ; 2/3 Aa c) 1/2 AA ; 1/2 Aa d) 1/3 AA ; 1/3 Aa e) none of the above 4. What is the probability IV-2 is heterozygous? a) 1/2 b) 5/9 c) 1/6 d) 11/18 e) 2/3 5. If IV-1 were to marry IV-2, what is the probability that their first child would be affected with the trait? a) 25% b) less than 1% c) less than 5% d) less than 10%
Md.Daniyal A.
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