Question

6.22. Consider steady-state operation of a chemostat. Assume that growth is substrate inhibited and that endogenous metabolism can be ignored such that we get the following: mu_{net} = frac{mu_m S}{K_S + S + S^2/K_I} a. Derive an expression for the residual substrate concentration (i.e., S) as a function of dilution rate and the kinetic parameters (mu_m, K_S, K_I). b. What are the implications for operation of a chemostat when the organism is subjected to substrate inhibition?

          6.22. Consider steady-state operation of a chemostat. Assume that growth is
substrate inhibited and that endogenous metabolism can be ignored such
that we get the following:

mu_{net} = frac{mu_m S}{K_S + S + S^2/K_I}

a. Derive an expression for the residual substrate concentration (i.e., S)
as a function of dilution rate and the kinetic parameters (mu_m, K_S, K_I).
b. What are the implications for operation of a chemostat when the
organism is subjected to substrate inhibition?

$6.22. Consider steady-state operation of a chemostat. Assume that growth is substrate inhibited and that endogenous metabolism can be ignored such that we get the following: munet = fracmum SKS + S + S^2/KI a. Derive an expression for the residual substrate concentration (i.e., S) as a function of dilution rate and the kinetic parameters (mum, KS, KI). b. What are the implications for operation of a chemostat when the organism is subjected to substrate inhibition?$

Added by Laura S.

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