A 1-week-old newborn girl returned for a pediatric appointment due to an apparent eye infection. On physical examination the newborn presented with profuse eye drainage and swollen eyelids. She was born via vaginal delivery at 39 weeks and discharged with the mother on day 2 of life. The mother refuse a topical prophylaxis eye ointment for the baby after birth. On day 4 of life the baby showed acute onset of left eye drainage. Drainage appeared on the right eye on day 5. On the day before the appointment, the drainage had become so profuse that the mother was cleaning the eyes several times per hour and her eyes were red. During the appointment a sample of the mucopurulent discharge was collected and sent to the laboratory for media culture. Gram stain of colonies showed Gram negative diplococci. Gram stain of diplococci from discharge sample 1. Which is the main organ system affected? Skin/Eyes 2. Which infection/disease is affecting the patient? [Select ] 3. Which pathogen is the most likely causative agent? Neisseria meningitidis
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The drainage started in the left eye on day 4 of life and spread to the right eye on day 5. The gram stain of the discharge showed gram-negative diplococci. Show more…
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You are doing a rotation in the hospital's clinical laboratory. A sample of cloudy cerebrospinal fluid (CSF) from a suspected meningitis case arrives, and you are told to Gram stain it and then plate it on blood agar and chocolate agar (look it up). In the Gram stain, you find gram-negative rods of varying size and shape. You also find a lot of bacteria inside phagocytic cells. They are not diplococci. Colonies grow on both of the plates you inoculated. Later, the charge nurse tells you that the patient, a 3-year-old girl, has not received any childhood vaccinations. 1. What is the most likely causative organism? WHY? 2. Why was the child's unvaccinated status helpful in diagnosis? 3. What is causing the cloudiness in the CSF? 4. What other types of infections can this organism cause in children?
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