Question

2. Answer the following questions regarding the peptide Cys-Tyr-Ile-Gln-Asn-Val-Cys-Gly (25 pts) (a) What is the sequence of amino acids written using the single letter code (b) Draw the structure of the peptide as it would exist at pH 7. Be sure to draw any disulfide bonds that could form. (c) Label the N-terminus of the peptide you drew in 1b. (d) Circle a peptide bond in the peptide you drew in 1b. (e) Calculate the overall charge of the peptide at pH 1, 9, 11, and 14 using the pKa values listed in Voet, Voet, Pratt on pages 82-83. (f) Calculate the pI of this peptide.

          2. Answer the following questions regarding the peptide Cys-Tyr-Ile-Gln-Asn-Val-Cys-Gly (25 pts)
(a) What is the sequence of amino acids written using the single letter code
(b) Draw the structure of the peptide as it would exist at pH 7. Be sure to draw any disulfide bonds that could form.
(c) Label the N-terminus of the peptide you drew in 1b.
(d) Circle a peptide bond in the peptide you drew in 1b.
(e) Calculate the overall charge of the peptide at pH 1, 9, 11, and 14 using the pKa values listed in Voet, Voet, Pratt on pages 82-83.
(f) Calculate the pI of this peptide.

2. Answer the following questions regarding the peptide Cys-Tyr-Ile-Gln-Asn-Val-Cys-Gly (25 pts)
(a) What is the sequence of amino acids written using the single letter code
(b) Draw the structure of the peptide as it would exist at pH 7. Be sure to draw any disulfide bonds that could form.
(c) Label the N-terminus of the peptide you drew in 1b.
(d) Circle a peptide bond in the peptide you drew in 1b.
(e) Calculate the overall charge of the peptide at pH 1, 9, 11, and 14 using the pKa values listed in Voet, Voet, Pratt on pages 82-83.
(f) Calculate the pI of this peptide.

Added by Andrea G.

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