Describe in some detail how DNA polymerases "proofread" a DNA strand and correct errors due to mis-incorporated bases. Detail the function of a Trans Lesion (TLS) DNA polymerase and the difference between the function of this polymerase and the normal Replicative DNA polymerase used at the replication fork with regard to the DNA proofreading and replication functions.
Added by Javier S.
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DNA polymerases are enzymes that synthesize new DNA strands by adding nucleotides to the growing chain, using a template DNA strand as a guide. During this process, they can make errors by incorporating incorrect nucleotides. Show more…
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