Hexokinase is a Michaelis-Menten enzyme that catalyzes the first reaction in glycolysis. The two curves in a graph show the activity of the hexokinase isoform expressed in skeletal muscle cells (line is above, higher) compared to liver cells (line is below, less). From the information in this graph, which of the following statements is supported? Glucose is an allosteric activator of liver hexokinase. The initial velocity of skeletal muscle hexokinase reaches equilibrium more quickly than liver hexokinase. Positive cooperativity is a characteristic of skeletal muscle hexokinase but not liver hexokinase. Liver hexokinase has a lower affinity for substrate than skeletal muscle hexokinase.
Added by Naomi S.
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The graph shows that the activity of hexokinase in skeletal muscle cells is higher than in liver cells. This could be due to a number of factors, including a higher concentration of the enzyme, a higher affinity for the substrate, or a faster turnover rate. Show more…
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