In comparing fatty acid biosynthesis with β-oxidation of fatty acids, which of the following statements is FALSE? Acyl-CoA derivatives are intermediates in both systems. Fatty acid biosynthesis uses NADPH, whereas β-oxidation uses NAD+ and FAD. The condensation of two moles of acetyl-CoA is more rapid in bicarbonate buffer than in phosphate buffer at the same pH; the cleavage of acetoacetyl-CoA proceeds equally well in either buffer. Fatty acid synthesis is catalyzed by cytosolic enzymes; fatty acid degradation by mitochondrial enzymes. Breakdown of a 16C fatty acid produces more than enough energy to rebuild that fatty acid.
Added by Martin H.
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Step 1: Acyl-CoA derivatives are intermediates in both fatty acid biosynthesis and β-oxidation of fatty acids. Show more…
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