In the nucleotide excision repair (NER) system, select the complex that recognizes damaged DNA, followed by the proteins that act to remove the damaged DNA. Multiple choice question. UvrC/UvrD complex; UvrA (helicase) and UvrB (endonuclease) UvrA/UvrB complex; UvrC (helicase) and UvrD (endonuclease) UvrA/UvrB complex; UvrC (endonuclease) and UvrD (helicase) UvrC/UvrD complex; UvrA (endonuclease) and UvrB (helicase)
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During nucleotide excision repair (NER), which of the following is true? a) removal of uracil base from the DNA strand b) recognition of the DNA distortion by the UvrAB complex c) unwinding of sister chromatid which is used as a template for the damaged strand d) hemi-methylated DNA is used to determine the correct base 2. Which are examples of damage found in DNA? a) phosphodiester strand breaks due to X-rays b) thymine-thymine dimers formed by UV radiation c) deamination of cytosine to uracil d) alkylating agents modifying a guanine
Madhur L.
If a mutation eliminated the function of UvrC, which aspect of nucleotide excision repair would not work? a. sensing a damaged DNA site b. endonuclease cleavage of the damaged strand c. removal of the damaged strand d. synthesis of a new strand, using the undamaged strand as a template e. none of the above
Sri K.
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